His drawings in 1944 recorded the ravages of German-occupied Rome in realistic detail.Those images, often likened to German Expressionist works, were featured in his first solo exhibition at Rome's Galleria La Margherita in 1945. Meanwhile, he collaborated as a designer with many political-literary reviews done as poetic documentaries, relating to the cinema of Rossellini and Vittorio de Sica.
In 1956 he co-founded, with other intellectuals, the review Citta Aperta ("City Opened"), a magazine concerning the city culture’s problems.At this time, his work had begun to focus on life in the harsh neighborhoods of Rome's periphery, displaying a connection with the films and literature of Italian Neorealism.
Renzo Vespignani exhibited works across Italy and had participated in the Venice Biennale four times. A 1985 exhibition at the French Academy in Rome examined the rapport between Vespignani's work and that of the Neorealist poet and filmmaker Pier Paolo Pasolini.
After the 1970s, Vespignani rarely exhibited abroad, although two bodies of his work from the 1990s, Manhattan Transfer and An Afternoon in Chelsea, had been inspired by visits to New York City.
Renzo Vespignani died on April 26, 2001, while undergoing surgery.Wikipedia